The System for Award Management (SAM) is a mandatory registration system for businesses, organizations, and individuals seeking to enter into contracts with the U.S. federal government. Registration in SAM is essential for securing government procurement contracts, receiving federal grants, and supplying products and services through the GSA Schedule.

The General Services Administration (GSA) is the U.S. federal agency responsible for procurement, real estate management, and IT and service contracts for government agencies. Foreign companies seeking to enter into contracts with the U.S. federal government or register under the GSA Schedule must comply with GSA approval and contracting procedures.

The Food and Drug Administration (FDA) is a U.S. federal agency that regulates the safety and effectiveness of food, pharmaceuticals, medical devices, cosmetics, dietary supplements, animal products, biologics, and radiation-emitting devices. Foreign manufacturers seeking to distribute their products in the U.S. market must comply with FDA regulations.

The U.S. Department of Health and Human Services (HHS) is the federal agency responsible for public health, healthcare services, pharmaceutical and medical device regulation, and research funding in the United States. Foreign businesses, healthcare institutions, research organizations, and pharmaceutical and medical device manufacturers must comply with HHS regulations to operate in the U.S. or apply for research funding.

The U.S. Department of Education (ED) oversees education policies in the United States. Foreign educational institutions, education-related businesses, and online learning platforms must comply with ED regulations to operate programs or obtain certification in the U.S.

The U.S. Citizenship and Immigration Services (USCIS) oversees immigration, visas, work permits, and naturalization processes in the United States. Foreign businesses, investors, job seekers, family sponsors, and refugees must obtain USCIS approval for various immigration-related matters.

The United States Patent and Trademark Office (USPTO) is responsible for the registration and protection of patents, trademarks, and copyrights in the United States. Foreign businesses, inventors, and brand owners must obtain USPTO approval to safeguard their intellectual property (IP) in the U.S.

The U.S. Department of Transportation (DOT) oversees the management and regulation of the transportation system, including road, rail, aviation, maritime, and pipeline transport. Foreign manufacturers, transportation companies, logistics providers, and automotive and aircraft manufacturers must comply with DOT certifications and regulations to enter the U.S. market.

The National Aeronautics and Space Administration (NASA) is responsible for space exploration, aeronautics research, space technology development, satellite systems, and international collaboration projects. Foreign companies, research institutions, aerospace firms, and technology developers must comply with NASA regulations and contract procedures to participate in or collaborate on NASA projects.

The National Institutes of Health (NIH) is responsible for medical and life sciences research, public health advancements, and the development of pharmaceuticals and treatments. Foreign research institutes, pharmaceutical companies, biotech firms, and medical device manufacturers must comply with NIH regulations and procedures to apply for research grants, participate in research projects, or conduct clinical trials.

The Centers for Disease Control and Prevention (CDC) is responsible for public health protection, infectious disease prevention, vaccine regulation, biological material management, and global health cooperation. Foreign companies, research institutes, pharmaceutical firms, and medical device manufacturers must comply with CDC regulations to sell vaccines, diagnostic equipment, and medical products in the U.S. or engage in research collaborations.

The Small Business Administration (SBA) supports small businesses in the United States by providing loans, grant programs, government contracting opportunities, and business growth consulting. Foreign companies, startups, small manufacturers, and service providers must comply with SBA regulations to leverage SBA programs for entering the U.S. market or securing federal government contracts.

The U.S. International Trade Commission (USITC) is an independent federal agency responsible for trade investigations, intellectual property (IP) protection, anti-dumping and countervailing duty regulations, and market impact analysis of imported products. Foreign manufacturers, traders, exporters, and IP-owning companies must comply with USITC regulations to enter the U.S. market or respond to ITC investigations.

The Securities and Exchange Commission (SEC) oversees the U.S. securities and financial markets, regulating initial public offerings (IPOs), investment funds, securities issuance, and trading. Foreign companies, financial institutions, investment firms, and cryptocurrency-related businesses must comply with SEC regulations to issue securities or operate investment products in the U.S.

The U.S. Customs and Border Protection (CBP) is responsible for border security, import and export control, customs duties enforcement, and trade regulation compliance in the United States. Foreign manufacturers, exporters, importers, logistics providers, and e-commerce businesses must adhere to CBP regulations to distribute goods in the U.S. market.

The Drug Enforcement Administration (DEA) oversees the import, export, manufacturing, and distribution of controlled substances and chemicals, as well as the enforcement of laws against illegal drug trafficking. Foreign pharmaceutical companies, research institutes, healthcare facilities, and chemical manufacturers must comply with DEA’s strict regulations to manufacture, distribute, or research controlled substances and related products in the U.S.

The Federal Emergency Management Agency (FEMA) is responsible for disaster response, emergency procurement, federal grant assistance, recovery fund management, and emergency preparedness. Foreign manufacturers, suppliers, construction firms, and medical equipment manufacturers must work with FEMA regulations to secure emergency procurement contracts or participate in government grant and assistance programs.

The Consumer Product Safety Commission (CPSC) is a U.S. federal agency responsible for ensuring the safety of consumer products and preventing injuries and accidents related to these products. To sell toys, electronics, furniture, chemical-containing products, electrical devices, infant products, sports equipment, and other consumer goods in the U.S. market, companies must comply with CPSC regulations.

The U.S. Environmental Protection Agency (EPA) is responsible for protecting human health and the environment by enforcing regulations on air and water quality, chemical safety, and waste management. Companies manufacturing or importing chemical substances, pesticides, or disinfectants must comply with EPA regulations. Businesses seeking to market environmental products, register antimicrobials, or receive federal environmental approvals must work with the EPA to ensure regulatory compliance.

The Federal Trade Commission (FTC) is the U.S. federal agency responsible for protecting consumers and maintaining competition. It enforces laws that prevent deceptive advertising, unfair business practices, and fraudulent labeling or marketing. Companies offering consumer goods, cosmetics, textiles, or dietary supplements must ensure their claims, labels, and advertising comply with FTC regulations to avoid legal enforcement actions.